Practice problems

# Question
1 The recommended dose of a drug is 4.5 ml/kg. How many tablespoonful’s will a patient weighing 170 lb need? (Round down if necessary)
2 The pediatric dose for ampicillin is 150 mg/kg/day. How many ml of an injection containing 250 mg/ 15 ml should be administered to a child weighing 20 kg?
3 CR, is a female patient who weighs 71 kg and is 158 cm tall. She is being treated with digoxin. The dose of digoxin is based on IBW. What is the patient dose in μg , if digoxin dose is 23 μg/kg?
4 The pediatric dose of a drug is 100 mg/m2. Using the nomogram method, calculate the dose for a child weighing 12 kg and measuring 118 cm.
5 If the adult dose of a drug is 100 mg/m2, using the Mostellar equation, calculated the dose for a patient weighing 288 lb and measuring 4' 4"
6 The recommended adult dose of a drug is 100 mg/day. What should be the dose for a patient with BSA of 1.8 m2?
7 Using the nomogram method, calculate the dose of doxurubin 50 mg/m2 for a patient who weighs 41 kg and is 106 cm tall.
8 A 60 year old female patient is prescribed an antiarrhythmic drug at a dose of 500 μg PO q 12h. The patient serum creatinine is 3.10 mg/dl, she weighs 189 lb and measures 5' 3". The following are dosing guidelines for the drug
CrCl (ml / min) Drug Dose
> 60 500 μg PO q 12h.
40 - < 60 250 μg PO q 12h.
20 - < 40 125 μg PO q 12h.
<= 20 Contraindicated
a) What is the patient’s calculated creatinine clearance?
b) What dose would you recommend?
9 VAD is a combination of three chemotherapy drugs used to treat myeloma. A 322 lb, 5 feet 5 inches patient receives the following regimen:
Cycle: 28 days
Vincristine 0.4 mg/day IV on days 1 through 4
Doxorubicin 9 mg/m2/day IV on days 1 through 4
Dexamethasone 40 mg/day PO on days 1-4, 9-12, 17-20

Calculate the total quantity of each drug required per cycle. (use the nomogram method to calculate the BSA)
10 AC regimen is a combination of two chemotherapy drugs used to treat Breast cancer. A female patient with a BSA of A 2.1 m2 receives the following regimen:
Cycle: 3 weeks, repeat 4-6 cycles
Doxorubicin: 60 mg/m2/day IV on day 1
Cyclophosphamide: 600 mg/m2/day IV on day 1
Calculate the total quantity of each drug required in 2 cycles.
11 When using a dropper you find that 84 drops of a mixture measure 7 ml. How many drops/ml is the dropper calibrated to deliver?
12 A patient drops off a prescription for prednisone. The prescription calls for:
Week 1: 60 mg PO q day
Week 2: 40 mg PO q day
Week 3: 30 mg PO q day
Week 4: 30 mg PO q day
How many 20 mg tablets would provide for the 4 week treatment?
13 Children’s Ibuprofen suspension is available as 100 mg/5 ml. Dose for a 71 lb child is 12.5 ml. The dropper contains 10 drops/ml. How many drops is the child taking per dose?
14 A 2.25 g of sample of drug contains 50 doses. What is the dose of drug in mg?
15 The recommended dose of a cough syrup of 1 teaspoon , how many doses are contained in an 1 fluid ounce bottle? (Round down if necessary)
16 Calculate the volume of U-500 required to administer 3000 units of insulin.
17 The content of a vial of penicillin G potassium weighs 700 mg and represents 5000000 units. How many milligrams are needed to prepared 30 g of an ointment that is to contain 241000 units of penicillin G potassium per gram?

Answers

The Answer to question 1 is: 23

The Answer to question 2 is: 180.00 ml

The Answer to question 3 is: 1152.30 μg

The Answer to question 4 is: 65.63 mg

The Answer to question 5 is: 219.16 mg

The Answer to question 6 is: 104.05 mg

The Answer to question 7 is: 51.18 mg

The Answer to question 8 is: a) 15.96 ml/min b) Contraindicated

The Answer to question 9 is: vincristine = 1.6 mg, doxorubicin 87.27 mg, dexamethasone = 480.00 mg

The Answer to question 10 is: doxorubicin = 252 mg, Cyclophosphamide = 2520 mg

The Answer to question 11 is: 12 drops/ml

The Answer to question 12 is: 56 tablets

The Answer to question 13 is: 125 drops

The Answer to question 14 is: 45.00 mg

The Answer to question 15 is: 5 doses

The Answer to question 16 is: 6.00 ml

The Answer to question 17 is: 1012.20 mg